Multiple sequence alignment with the Clustal series of programs
نویسندگان
چکیده
منابع مشابه
Multiple sequence alignment with the Clustal series of programs
The Clustal series of programs are widely used in molecular biology for the multiple alignment of both nucleic acid and protein sequences and for preparing phylogenetic trees. The popularity of the programs depends on a number of factors, including not only the accuracy of the results, but also the robustness, portability and user-friendliness of the programs. New features include NEXUS and FAS...
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An approach for performing multiple alignments of large numbers of amino acid or nucleotide sequences is described. The method is based on first deriving a phylogenetic tree from a matrix of all pairwise sequence similarity scores, obtained using a fast pairwise alignment algorithm. Then the multiple alignment is achieved from a series of pairwise alignments of clusters of sequences, following ...
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For both the computational biologist and the research biologist, the use of multiple sequence alignment (MSA) programs to simultaneously align multiple sequences of nucleic acids or proteins has become de rigueur. Successful alignments are used in a number of applications, such as (1) phylogenetic analysis, as a predictor of evolutionary relationships; (2) identifying conserved motifs and domai...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2003
ISSN: 1362-4962
DOI: 10.1093/nar/gkg500